dCas9-Based Scn1a Gene Activation Restores Inhibitory Interneuron Excitability and Attenuates Seizures in Dravet Syndrome Mice. (Record no. 30196812)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02184 a2200625 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250518063922.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 202012s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1525-0024 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1016/j.ymthe.2019.08.018 |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Colasante, Gaia |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20201221 |
| 245 00 - TITLE STATEMENT | |
| Title | dCas9-Based Scn1a Gene Activation Restores Inhibitory Interneuron Excitability and Attenuates Seizures in Dravet Syndrome Mice. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Molecular therapy : the journal of the American Society of Gene Therapy |
| Date of publication, distribution, etc. | 01 2020 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 235-253 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article; Research Support, Non-U.S. Gov't |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Action Potentials |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Animals |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | CRISPR-Associated Protein 9 |
| General subdivision | genetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cell Line, Tumor |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Disease Models, Animal |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Epilepsies, Myoclonic |
| General subdivision | therapy |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Female |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | GABAergic Neurons |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Genetic Therapy |
| General subdivision | methods |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Hippocampus |
| General subdivision | cytology |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Interneurons |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mice |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mice, Inbred C57BL |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mice, Transgenic |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | NAV1.1 Voltage-Gated Sodium Channel |
| General subdivision | genetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Seizures |
| General subdivision | therapy |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Transcriptional Activation |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Treatment Outcome |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lignani, Gabriele |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Brusco, Simone |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Di Berardino, Claudia |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Carpenter, Jenna |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Giannelli, Serena |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Valassina, Nicholas |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bido, Simone |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ricci, Raffaele |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Castoldi, Valerio |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Marenna, Silvia |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Church, Timothy |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Massimino, Luca |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Morabito, Giuseppe |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Benfenati, Fabio |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Schorge, Stephanie |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Leocani, Letizia |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kullmann, Dimitri M |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Broccoli, Vania |
| 773 0# - HOST ITEM ENTRY | |
| Title | Molecular therapy : the journal of the American Society of Gene Therapy |
| Related parts | vol. 28 |
| -- | no. 1 |
| -- | p. 235-253 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1016/j.ymthe.2019.08.018">https://doi.org/10.1016/j.ymthe.2019.08.018</a> |
| Public note | Available from publisher's website |
No items available.