Targeting p16-induced senescence prevents cigarette smoke-induced emphysema by promoting IGF1/Akt1 signaling in mice. [electronic resource]
Producer: 20200414Description: 307 p. digitalISSN:- 2399-3642
- Alveolar Epithelial Cells -- metabolism
- Animals
- Cell Proliferation
- Cellular Senescence
- Cyclin-Dependent Kinase Inhibitor p16 -- genetics
- Cytokines -- metabolism
- Emphysema -- etiology
- Insulin-Like Growth Factor I -- genetics
- Lung -- metabolism
- Mice, Inbred C57BL
- Models, Biological
- Promoter Regions, Genetic -- genetics
- Proto-Oncogene Proteins c-akt -- genetics
- Pulmonary Disease, Chronic Obstructive -- metabolism
- RNA, Messenger -- genetics
- Signal Transduction
- Smoking -- adverse effects
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
There are no comments on this title.
Log in to your account to post a comment.