Excess hepsin proteolytic activity limits oncogenic signaling and induces ER stress and autophagy in prostate cancer cells. [electronic resource]
Producer: 20200730Description: 601 p. digitalISSN:- 2041-4889
- Animals
- Autophagy -- genetics
- Carcinogenesis -- genetics
- Cinnamates -- pharmacology
- Endoplasmic Reticulum Stress -- drug effects
- Endoplasmic Reticulum-Associated Degradation -- genetics
- Gene Expression Regulation, Neoplastic -- drug effects
- Heterografts
- Humans
- Macrolides -- pharmacology
- Male
- Mice
- Microtubule-Associated Proteins -- genetics
- Neoplastic Stem Cells -- metabolism
- PC-3 Cells
- Prostatic Neoplasms -- genetics
- Sequestosome-1 Protein -- genetics
- Serine Endopeptidases -- genetics
- Thiourea -- analogs & derivatives
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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