Paricalcitol accelerates BACE1 lysosomal degradation and inhibits calpain-1 dependent neuronal loss in APP/PS1 transgenic mice. [electronic resource]
Producer: 20191217Description: 393-407 p. digitalISSN:- 2352-3964
- 8-Hydroxy-2'-Deoxyguanosine -- metabolism
- Alzheimer Disease -- drug therapy
- Amyloid Precursor Protein Secretases -- genetics
- Amyloid beta-Peptides -- genetics
- Animals
- Aspartic Acid Endopeptidases -- genetics
- Brain -- metabolism
- Calpain -- genetics
- Disease Models, Animal
- Ergocalciferols -- pharmacology
- Gene Expression Regulation -- drug effects
- Humans
- Low Density Lipoprotein Receptor-Related Protein-1 -- genetics
- Lysosomes -- drug effects
- Mice
- Mice, Transgenic
- Mitochondria -- metabolism
- Neurons -- drug effects
- Oligopeptides -- genetics
- Presenilin-1 -- genetics
- Proteolysis -- drug effects
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Publication Type: Journal Article
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