Skeletal muscle PGC-1α1 reroutes kynurenine metabolism to increase energy efficiency and fatigue-resistance. [electronic resource]
Producer: 20190705Description: 2767 p. digitalISSN:- 2041-1723
- Adaptation, Physiological
- Animals
- Aspartate Aminotransferases -- metabolism
- Aspartic Acid -- metabolism
- Carbidopa -- pharmacology
- Cell Respiration -- drug effects
- Energy Metabolism -- drug effects
- Fatigue -- physiopathology
- Glycolysis -- physiology
- Kynurenine -- metabolism
- Malates -- metabolism
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Mitochondria -- drug effects
- Models, Animal
- Muscle, Skeletal -- metabolism
- Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha -- genetics
- Physical Conditioning, Animal -- physiology
- Protein Isoforms -- genetics
- Transaminases -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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