Preclinical rationale for entinostat in embryonal rhabdomyosarcoma. [electronic resource]
Producer: 20200504Description: 12 p. digitalISSN:- 2044-5040
- Adolescent
- Animals
- Antineoplastic Agents, Phytogenic -- administration & dosage
- Antineoplastic Combined Chemotherapy Protocols -- administration & dosage
- Benzamides -- administration & dosage
- CRISPR-Cas Systems
- Cell Differentiation -- drug effects
- Cell Line, Tumor
- Cellular Reprogramming -- drug effects
- Child
- Child, Preschool
- Drug Screening Assays, Antitumor
- Female
- Histone Deacetylase 1 -- antagonists & inhibitors
- Histone Deacetylase Inhibitors -- administration & dosage
- Humans
- Male
- Mice
- Mice, Inbred NOD
- Mice, SCID
- Pyridines -- administration & dosage
- RNA-Seq
- Rhabdomyosarcoma, Alveolar -- drug therapy
- Rhabdomyosarcoma, Embryonal -- drug therapy
- Tumor Burden -- drug effects
- Tumor Microenvironment -- drug effects
- Vincristine -- administration & dosage
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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