Preclinical rationale for entinostat in embryonal rhabdomyosarcoma.

Bharathy, Narendra

Preclinical rationale for entinostat in embryonal rhabdomyosarcoma. [electronic resource] - Skeletal muscle 05 2019 - 12 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

2044-5040

10.1186/s13395-019-0198-x doi


Adolescent
Animals
Antineoplastic Agents, Phytogenic--administration & dosage
Antineoplastic Combined Chemotherapy Protocols--administration & dosage
Benzamides--administration & dosage
CRISPR-Cas Systems
Cell Differentiation--drug effects
Cell Line, Tumor
Cellular Reprogramming--drug effects
Child
Child, Preschool
Drug Screening Assays, Antitumor
Female
Histone Deacetylase 1--antagonists & inhibitors
Histone Deacetylase Inhibitors--administration & dosage
Humans
Male
Mice
Mice, Inbred NOD
Mice, SCID
Pyridines--administration & dosage
RNA-Seq
Rhabdomyosarcoma, Alveolar--drug therapy
Rhabdomyosarcoma, Embryonal--drug therapy
Tumor Burden--drug effects
Tumor Microenvironment--drug effects
Vincristine--administration & dosage
Xenograft Model Antitumor Assays