Aging Human Hematopoietic Stem Cells Manifest Profound Epigenetic Reprogramming of Enhancers That May Predispose to Leukemia. [electronic resource]
Producer: 20200805Description: 1080-1101 p. digitalISSN:- 2159-8290
- Cell Differentiation -- genetics
- Cellular Reprogramming -- genetics
- Cellular Senescence -- genetics
- Cytosine -- metabolism
- DNA Methylation
- Disease Susceptibility
- Enhancer Elements, Genetic
- Epigenesis, Genetic
- Gene Expression Profiling
- Gene Expression Regulation, Leukemic
- Hematopoietic Stem Cells -- metabolism
- Histones -- metabolism
- Humans
- Kruppel-Like Factor 6 -- genetics
- Leukemia -- genetics
- Promoter Regions, Genetic
- Transcription Factors -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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