In vitro and computational studies showed that perezone inhibits PARP-1 and induces changes in the redox state of K562 cells. [electronic resource]
Producer: 20200316Description: 225-234 p. digitalISSN:- 1096-0384
- Apoptosis -- drug effects
- Asteraceae -- chemistry
- Cell Cycle -- drug effects
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- Humans
- K562 Cells
- Molecular Docking Simulation
- Molecular Dynamics Simulation
- Oxidation-Reduction -- drug effects
- Poly (ADP-Ribose) Polymerase-1 -- antagonists & inhibitors
- Poly(ADP-ribose) Polymerase Inhibitors -- isolation & purification
- Sesquiterpenes -- isolation & purification
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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