Depletion of B cells rejuvenates the peripheral B-cell compartment but is insufficient to restore immune competence in aging. [electronic resource]
Producer: 20200707Description: e12959 p. digitalISSN:- 1474-9726
- Adolescent
- Adult
- Aged
- Aging -- immunology
- Animals
- Antigens, CD20 -- genetics
- Antineoplastic Agents, Immunological -- therapeutic use
- B-Lymphocytes -- immunology
- Bone Marrow Cells -- immunology
- Female
- Healthy Volunteers
- Humans
- Lymphocyte Depletion -- methods
- Lymphoma, B-Cell -- blood
- Lymphopoiesis -- immunology
- Male
- Mice
- Mice, Inbred BALB C
- Mice, Transgenic
- Middle Aged
- Prospective Studies
- Rejuvenation -- physiology
- Rituximab -- therapeutic use
- Young Adult
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Publication Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
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