Preoperative anxiety-induced glucocorticoid signaling reduces GABAergic markers in spinal cord and promotes postoperative hyperalgesia by affecting neuronal PAS domain protein 4. [electronic resource]
Producer: 20200526Description: 1744806919850383 p. digitalISSN:- 1744-8069
- Animals
- Anxiety -- complications
- Basic Helix-Loop-Helix Transcription Factors -- metabolism
- Biomarkers -- metabolism
- Corticosterone -- blood
- Dependovirus -- metabolism
- Down-Regulation -- drug effects
- Glucocorticoids -- metabolism
- Hyperalgesia -- complications
- Injections, Spinal
- Male
- Mifepristone -- pharmacology
- Neurons -- drug effects
- Postoperative Care
- Preoperative Care
- RNA Interference
- RNA, Messenger -- genetics
- Rats, Sprague-Dawley
- Signal Transduction -- drug effects
- Spinal Cord -- metabolism
- Spironolactone -- pharmacology
- Stress, Psychological -- blood
- Up-Regulation -- drug effects
- gamma-Aminobutyric Acid -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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