In vivo genome editing rescues photoreceptor degeneration via a Cas9/RecA-mediated homology-directed repair pathway. [electronic resource]
Producer: 20200427Description: eaav3335 p. digitalISSN:- 2375-2548
- Animals
- CRISPR-Cas Systems -- genetics
- Cyclic Nucleotide Phosphodiesterases, Type 6 -- genetics
- DNA Repair
- Electroporation
- Gene Editing -- methods
- Humans
- Mice
- Mice, Inbred C57BL
- Rec A Recombinases -- metabolism
- Retinal Degeneration -- therapy
- Retinal Rod Photoreceptor Cells -- metabolism
- RNA, Guide, CRISPR-Cas Systems
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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