Metformin inhibits IL-6 signaling by decreasing IL-6R expression on multiple myeloma cells. [electronic resource]
Producer: 20200601Description: 2695-2709 p. digitalISSN:- 1476-5551
- Antibodies, Monoclonal -- pharmacology
- Biomarkers, Tumor -- metabolism
- Bortezomib -- pharmacology
- Cell Line, Tumor
- Dexamethasone -- pharmacology
- Enzyme-Linked Immunosorbent Assay
- Gene Expression Profiling
- Gene Expression Regulation, Neoplastic
- Humans
- Inhibitory Concentration 50
- Interleukin-6 -- metabolism
- Metformin -- pharmacology
- Multiple Myeloma -- metabolism
- Phenformin -- pharmacology
- Plasma Cells -- pathology
- Receptors, Interleukin-6 -- metabolism
- Sequence Analysis, RNA
- Signal Transduction
- Syndecan-1 -- metabolism
- Thalidomide -- analogs & derivatives
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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