Metformin inhibits IL-6 signaling by decreasing IL-6R expression on multiple myeloma cells.
Mishra, Ameet K
Metformin inhibits IL-6 signaling by decreasing IL-6R expression on multiple myeloma cells. [electronic resource] - Leukemia 11 2019 - 2695-2709 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1476-5551
10.1038/s41375-019-0470-4 doi
Antibodies, Monoclonal--pharmacology
Biomarkers, Tumor--metabolism
Bortezomib--pharmacology
Cell Line, Tumor
Dexamethasone--pharmacology
Enzyme-Linked Immunosorbent Assay
Gene Expression Profiling
Gene Expression Regulation, Neoplastic
Humans
Inhibitory Concentration 50
Interleukin-6--metabolism
Metformin--pharmacology
Multiple Myeloma--metabolism
Phenformin--pharmacology
Plasma Cells--pathology
Receptors, Interleukin-6--metabolism
Sequence Analysis, RNA
Signal Transduction
Syndecan-1--metabolism
Thalidomide--analogs & derivatives
Metformin inhibits IL-6 signaling by decreasing IL-6R expression on multiple myeloma cells. [electronic resource] - Leukemia 11 2019 - 2695-2709 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1476-5551
10.1038/s41375-019-0470-4 doi
Antibodies, Monoclonal--pharmacology
Biomarkers, Tumor--metabolism
Bortezomib--pharmacology
Cell Line, Tumor
Dexamethasone--pharmacology
Enzyme-Linked Immunosorbent Assay
Gene Expression Profiling
Gene Expression Regulation, Neoplastic
Humans
Inhibitory Concentration 50
Interleukin-6--metabolism
Metformin--pharmacology
Multiple Myeloma--metabolism
Phenformin--pharmacology
Plasma Cells--pathology
Receptors, Interleukin-6--metabolism
Sequence Analysis, RNA
Signal Transduction
Syndecan-1--metabolism
Thalidomide--analogs & derivatives