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  2. Details for: Structure Overhaul Affords a Potent Purine PI3Kδ Inhibitor with Improved Tolerability.
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Structure Overhaul Affords a Potent Purine PI3Kδ Inhibitor with Improved Tolerability. [electronic resource]

By:
  • Methot, Joey L
Contributor(s):
  • Zhou, Hua
  • Kattar, Sam D
  • McGowan, Meredeth A
  • Wilson, Kevin
  • Garcia, Yudith
  • Deng, Yongi
  • Altman, Michael
  • Fradera, Xavier
  • Lesburg, Charles
  • Fischmann, Thierry
  • Li, Chaomin
  • Alves, Steve
  • Shah, Sanjiv
  • Fernandez, Rafael
  • Goldenblatt, Peter
  • Hill, Armetta
  • Shaffer, Lynsey
  • Chen, Dapeng
  • Tong, Vince
  • McLeod, Robbie L
  • Yu, Hongshi
  • Bass, Alan
  • Kemper, Ray
  • Gatto, Nicholas T
  • LaFranco-Scheuch, Lisa
  • Trotter, Benjamin Wesley
  • Guzi, Timothy
  • Katz, Jason D
Producer: 20200622Description: 4370-4382 p. digitalISSN:
  • 1520-4804
Subject(s):
  • Animals
  • Class Ia Phosphatidylinositol 3-Kinase -- metabolism
  • Dogs
  • Drug Design
  • HeLa Cells
  • Humans
  • Male
  • Protein Kinase Inhibitors -- chemical synthesis
  • Purines -- chemical synthesis
  • Pyrrolidines -- chemical synthesis
  • Rats, Wistar
Online resources:
  • Available from publisher's website
In: Journal of medicinal chemistry vol. 62
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Publication Type: Journal Article

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Structure Overhaul Affords a Potent Purine PI3Kδ Inhibitor with Improved Tolerability.

APA

Methot J. L., Zhou H., Kattar S. D., McGowan M. A., Wilson K., Garcia Y., Deng Y., Altman M., Fradera X., Lesburg C., Fischmann T., Li C., Alves S., Shah S., Fernandez R., Goldenblatt P., Hill A., Shaffer L., Chen D., Tong V., McLeod R. L., Yu H., Bass A., Kemper R., Gatto N. T., LaFranco-Scheuch L., Trotter B. W., Guzi T. & Katz J. D. (20200622). Structure Overhaul Affords a Potent Purine PI3Kδ Inhibitor with Improved Tolerability. : Journal of medicinal chemistry.

Chicago

Methot Joey L, Zhou Hua, Kattar Sam D, McGowan Meredeth A, Wilson Kevin, Garcia Yudith, Deng Yongi, Altman Michael, Fradera Xavier, Lesburg Charles, Fischmann Thierry, Li Chaomin, Alves Steve, Shah Sanjiv, Fernandez Rafael, Goldenblatt Peter, Hill Armetta, Shaffer Lynsey, Chen Dapeng, Tong Vince, McLeod Robbie L, Yu Hongshi, Bass Alan, Kemper Ray, Gatto Nicholas T, LaFranco-Scheuch Lisa, Trotter Benjamin Wesley, Guzi Timothy and Katz Jason D. 20200622. Structure Overhaul Affords a Potent Purine PI3Kδ Inhibitor with Improved Tolerability. : Journal of medicinal chemistry.

Harvard

Methot J. L., Zhou H., Kattar S. D., McGowan M. A., Wilson K., Garcia Y., Deng Y., Altman M., Fradera X., Lesburg C., Fischmann T., Li C., Alves S., Shah S., Fernandez R., Goldenblatt P., Hill A., Shaffer L., Chen D., Tong V., McLeod R. L., Yu H., Bass A., Kemper R., Gatto N. T., LaFranco-Scheuch L., Trotter B. W., Guzi T. and Katz J. D. (20200622). Structure Overhaul Affords a Potent Purine PI3Kδ Inhibitor with Improved Tolerability. : Journal of medicinal chemistry.

MLA

Methot Joey L, Zhou Hua, Kattar Sam D, McGowan Meredeth A, Wilson Kevin, Garcia Yudith, Deng Yongi, Altman Michael, Fradera Xavier, Lesburg Charles, Fischmann Thierry, Li Chaomin, Alves Steve, Shah Sanjiv, Fernandez Rafael, Goldenblatt Peter, Hill Armetta, Shaffer Lynsey, Chen Dapeng, Tong Vince, McLeod Robbie L, Yu Hongshi, Bass Alan, Kemper Ray, Gatto Nicholas T, LaFranco-Scheuch Lisa, Trotter Benjamin Wesley, Guzi Timothy and Katz Jason D. Structure Overhaul Affords a Potent Purine PI3Kδ Inhibitor with Improved Tolerability. : Journal of medicinal chemistry. 20200622.

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