The CTLA-4 x OX40 bispecific antibody ATOR-1015 induces anti-tumor effects through tumor-directed immune activation. [electronic resource]
Producer: 20200707Description: 103 p. digitalISSN:- 2051-1426
- Animals
- Antibodies, Bispecific -- pharmacology
- CHO Cells
- CTLA-4 Antigen -- antagonists & inhibitors
- Cell Line, Tumor -- transplantation
- Cricetulus
- Disease Models, Animal
- Drug Screening Assays, Antitumor
- Female
- HEK293 Cells
- Humans
- Male
- Mice
- Mice, Transgenic
- Primary Cell Culture
- Proof of Concept Study
- Receptors, OX40 -- agonists
- T-Lymphocytes, Regulatory -- drug effects
- Urinary Bladder Neoplasms -- drug therapy
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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