Translation of Inhaled Drug Optimization Strategies into Clinical Pharmacokinetics and Pharmacodynamics Using GSK2292767A, a Novel Inhaled Phosphoinositide 3-Kinase [electronic resource]
Producer: 20191230Description: 443-453 p. digitalISSN:- 1521-0103
- Administration, Inhalation
- Adult
- Animals
- Bronchoalveolar Lavage
- Eosinophilia -- drug therapy
- Female
- Humans
- Indazoles -- administration & dosage
- Lung -- metabolism
- Male
- Mice
- Middle Aged
- Permeability
- Phosphoinositide-3 Kinase Inhibitors -- administration & dosage
- Safety
- Solubility
- Sputum -- drug effects
- Sulfonamides -- administration & dosage
- Translational Research, Biomedical
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Publication Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
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