DRAM1 regulates autophagy and cell proliferation via inhibition of the phosphoinositide 3-kinase-Akt-mTOR-ribosomal protein S6 pathway. [electronic resource]
Producer: 20190816Description: 28 p. digitalISSN:- 1478-811X
- Apoptosis
- Autophagy -- physiology
- Cell Proliferation
- Cell Survival
- HCT116 Cells
- HEK293 Cells
- HeLa Cells
- Humans
- Mechanistic Target of Rapamycin Complex 1 -- metabolism
- Membrane Proteins -- metabolism
- Phosphatidylinositol 3-Kinases -- metabolism
- Phosphorylation
- Proto-Oncogene Proteins c-akt -- metabolism
- Receptor, IGF Type 1 -- metabolism
- Ribosomal Protein S6 -- metabolism
- Signal Transduction
- Tumor Suppressor Protein p53 -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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