DRAM1 regulates autophagy and cell proliferation via inhibition of the phosphoinositide 3-kinase-Akt-mTOR-ribosomal protein S6 pathway.

Lu, Ting

DRAM1 regulates autophagy and cell proliferation via inhibition of the phosphoinositide 3-kinase-Akt-mTOR-ribosomal protein S6 pathway. [electronic resource] - Cell communication and signaling : CCS 03 2019 - 28 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1478-811X

10.1186/s12964-019-0341-7 doi


Apoptosis
Autophagy--physiology
Cell Proliferation
Cell Survival
HCT116 Cells
HEK293 Cells
HeLa Cells
Humans
Mechanistic Target of Rapamycin Complex 1--metabolism
Membrane Proteins--metabolism
Phosphatidylinositol 3-Kinases--metabolism
Phosphorylation
Proto-Oncogene Proteins c-akt--metabolism
Receptor, IGF Type 1--metabolism
Ribosomal Protein S6--metabolism
Signal Transduction
Tumor Suppressor Protein p53--metabolism