A Functional Landscape of Resistance to MEK1/2 and CDK4/6 Inhibition in NRAS-Mutant Melanoma. [electronic resource]
Producer: 20200207Description: 2352-2366 p. digitalISSN:- 1538-7445
- Antineoplastic Agents -- pharmacology
- Apoptosis
- Cell Cycle Checkpoints
- Cell Proliferation
- Cyclin-Dependent Kinase 4 -- antagonists & inhibitors
- Cyclin-Dependent Kinase 6 -- antagonists & inhibitors
- Drug Resistance, Neoplasm -- genetics
- GTP Phosphohydrolases -- genetics
- Humans
- MAP Kinase Kinase 1 -- antagonists & inhibitors
- MAP Kinase Kinase 2 -- antagonists & inhibitors
- Melanoma -- drug therapy
- Membrane Proteins -- genetics
- Mutation
- Phosphorylation
- Signal Transduction -- drug effects
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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