Targeting DNA Damage Response Promotes Antitumor Immunity through STING-Mediated T-cell Activation in Small Cell Lung Cancer. [electronic resource]
Producer: 20200601Description: 646-661 p. digitalISSN:- 2159-8290
- Animals
- Apoptosis -- drug effects
- B7-H1 Antigen -- antagonists & inhibitors
- CD8-Positive T-Lymphocytes -- drug effects
- Cell Proliferation -- drug effects
- DNA Damage
- Female
- Humans
- Interferon Regulatory Factor-3 -- genetics
- Lung Neoplasms -- drug therapy
- Lymphocyte Activation -- drug effects
- Membrane Proteins -- genetics
- Mice
- Mice, Nude
- Phthalazines -- pharmacology
- Piperazines -- pharmacology
- Poly(ADP-ribose) Polymerase Inhibitors -- pharmacology
- Protein Kinase Inhibitors -- pharmacology
- Protein Serine-Threonine Kinases -- genetics
- Pyrazines -- pharmacology
- Pyrazoles -- pharmacology
- Random Allocation
- Small Cell Lung Carcinoma -- drug therapy
- T-Lymphocytes, Cytotoxic -- drug effects
- Tumor Cells, Cultured
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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