PCK1 negatively regulates cell cycle progression and hepatoma cell proliferation via the AMPK/p27 [electronic resource]
Producer: 20190603Description: 50 p. digitalISSN:- 1756-9966
- AMP-Activated Protein Kinases -- genetics
- Animals
- Calcium-Binding Proteins -- metabolism
- Carcinoma, Hepatocellular -- drug therapy
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cyclin-Dependent Kinases -- metabolism
- Down-Regulation
- E2F Transcription Factors -- metabolism
- G1 Phase Cell Cycle Checkpoints -- drug effects
- Gene Knockdown Techniques
- Glucose -- metabolism
- Humans
- Hypoglycemic Agents -- pharmacology
- Intracellular Signaling Peptides and Proteins -- genetics
- Liver Neoplasms -- drug therapy
- Male
- Metformin -- pharmacology
- Mice
- Phosphoenolpyruvate Carboxykinase (GTP) -- genetics
- Up-Regulation
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article
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