Nrf2 deficiency exacerbates frailty and sarcopenia by impairing skeletal muscle mitochondrial biogenesis and dynamics in an age-dependent manner. [electronic resource]
Producer: 20200601Description: 61-73 p. digitalISSN:- 1873-6815
- Aging -- genetics
- Animals
- Disease Models, Animal
- Frailty -- etiology
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Mitochondria, Muscle -- pathology
- Mitochondrial Dynamics
- Muscle, Skeletal -- pathology
- NF-E2-Related Factor 2 -- deficiency
- Organelle Biogenesis
- RNA, Messenger -- genetics
- Sarcopenia -- etiology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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