Novel small molecule IL-6 inhibitor suppresses autoreactive Th17 development and promotes T [electronic resource]
Producer: 20200218Description: 215-225 p. digitalISSN:- 1365-2249
- Adoptive Transfer -- methods
- Animals
- CD4-Positive T-Lymphocytes -- drug effects
- Encephalomyelitis, Autoimmune, Experimental -- drug therapy
- Humans
- Interleukin-6 -- antagonists & inhibitors
- Mice
- Mice, Inbred C57BL
- Mice, Transgenic
- Multiple Sclerosis -- drug therapy
- Myelin Sheath -- metabolism
- STAT3 Transcription Factor -- metabolism
- Signal Transduction -- drug effects
- Small Molecule Libraries -- pharmacology
- T-Lymphocytes, Regulatory -- drug effects
- Th17 Cells -- drug effects
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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