Bone marrow mesenchymal stem cell transplantation exerts neuroprotective effects following cerebral ischemia/reperfusion injury by inhibiting autophagy via the PI3K/Akt pathway. [electronic resource]
Producer: 20200611Description: 124-132 p. digitalISSN:- 1872-6240
- Animals
- Apoptosis -- drug effects
- Autophagy -- physiology
- Bone Marrow -- metabolism
- Brain Ischemia -- metabolism
- Cell Death -- drug effects
- Cell Survival -- drug effects
- Infarction, Middle Cerebral Artery -- pathology
- Male
- Mesenchymal Stem Cell Transplantation -- methods
- Mesenchymal Stem Cells -- metabolism
- Neuroprotective Agents -- metabolism
- Phosphatidylinositol 3-Kinases -- metabolism
- Proto-Oncogene Proteins c-akt -- metabolism
- Rats
- Rats, Sprague-Dawley
- Reperfusion Injury -- metabolism
- Signal Transduction -- drug effects
- TOR Serine-Threonine Kinases -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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