Bone marrow mesenchymal stem cell transplantation exerts neuroprotective effects following cerebral ischemia/reperfusion injury by inhibiting autophagy via the PI3K/Akt pathway.
He, He
Bone marrow mesenchymal stem cell transplantation exerts neuroprotective effects following cerebral ischemia/reperfusion injury by inhibiting autophagy via the PI3K/Akt pathway. [electronic resource] - Brain research 03 2019 - 124-132 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1872-6240
10.1016/j.brainres.2018.11.018 doi
Animals
Apoptosis--drug effects
Autophagy--physiology
Bone Marrow--metabolism
Brain Ischemia--metabolism
Cell Death--drug effects
Cell Survival--drug effects
Infarction, Middle Cerebral Artery--pathology
Male
Mesenchymal Stem Cell Transplantation--methods
Mesenchymal Stem Cells--metabolism
Neuroprotective Agents--metabolism
Phosphatidylinositol 3-Kinases--metabolism
Proto-Oncogene Proteins c-akt--metabolism
Rats
Rats, Sprague-Dawley
Reperfusion Injury--metabolism
Signal Transduction--drug effects
TOR Serine-Threonine Kinases--metabolism
Bone marrow mesenchymal stem cell transplantation exerts neuroprotective effects following cerebral ischemia/reperfusion injury by inhibiting autophagy via the PI3K/Akt pathway. [electronic resource] - Brain research 03 2019 - 124-132 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1872-6240
10.1016/j.brainres.2018.11.018 doi
Animals
Apoptosis--drug effects
Autophagy--physiology
Bone Marrow--metabolism
Brain Ischemia--metabolism
Cell Death--drug effects
Cell Survival--drug effects
Infarction, Middle Cerebral Artery--pathology
Male
Mesenchymal Stem Cell Transplantation--methods
Mesenchymal Stem Cells--metabolism
Neuroprotective Agents--metabolism
Phosphatidylinositol 3-Kinases--metabolism
Proto-Oncogene Proteins c-akt--metabolism
Rats
Rats, Sprague-Dawley
Reperfusion Injury--metabolism
Signal Transduction--drug effects
TOR Serine-Threonine Kinases--metabolism