Identification of a cellularly active SIRT6 allosteric activator. [electronic resource]
Producer: 20190508Description: 1118-1126 p. digitalISSN:- 1552-4469
- Allosteric Regulation
- Allosteric Site
- Animals
- Antineoplastic Agents -- pharmacology
- Benzoates -- pharmacology
- Carcinoma, Hepatocellular -- drug therapy
- Cell Line
- Cell Line, Tumor
- Crystallography, X-Ray
- Female
- High-Throughput Screening Assays -- methods
- Humans
- Liver Neoplasms -- drug therapy
- Mice, Inbred BALB C
- Molecular Dynamics Simulation
- Molecular Targeted Therapy
- Sirtuins -- chemistry
- Sulfur Compounds -- pharmacology
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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