Pharmacological inhibition of the NLRP3 inflammasome reduces blood pressure, renal damage, and dysfunction in salt-sensitive hypertension. [electronic resource]
Producer: 20200504Description: 776-787 p. digitalISSN:- 1755-3245
- Albuminuria -- etiology
- Animals
- Anti-Inflammatory Agents -- pharmacology
- Antihypertensive Agents -- pharmacology
- Blood Pressure -- drug effects
- Chemotaxis, Leukocyte -- drug effects
- Collagen -- metabolism
- Desoxycorticosterone Acetate
- Disease Models, Animal
- Fibrosis
- Furans -- pharmacology
- Heterocyclic Compounds, 4 or More Rings
- Hypertension -- etiology
- Indenes
- Inflammation Mediators -- metabolism
- Kidney -- drug effects
- Macrophages -- drug effects
- Male
- Mice, Inbred C57BL
- NLR Family, Pyrin Domain-Containing 3 Protein -- antagonists & inhibitors
- Nephrectomy
- Signal Transduction
- Sodium Chloride, Dietary
- Sulfonamides -- pharmacology
- Sulfones
- T-Lymphocyte Subsets -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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