Synthesis of Gemcitabine-Threonine Amide Prodrug Effective on Pancreatic Cancer Cells with Improved Pharmacokinetic Properties. [electronic resource]
Producer: 20181218ISSN:- 1420-3049
- Amino Acids
- Animals
- Antineoplastic Agents -- chemical synthesis
- Cell Line, Tumor
- Chemistry Techniques, Synthetic
- Chromatography, Liquid
- Chromatography, Thin Layer
- Deoxycytidine -- analogs & derivatives
- Disease Models, Animal
- Drug Monitoring
- Drug Stability
- Humans
- Magnetic Resonance Spectroscopy
- Pancreatic Neoplasms -- drug therapy
- Prodrugs -- chemical synthesis
- Tandem Mass Spectrometry
- Threonine -- chemistry
- Xenograft Model Antitumor Assays
- Gemcitabine
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Publication Type: Journal Article
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