Crizotinib treatment for patients with EGFR mutation positive NSCLC that acquire cMET amplification after EGFR TKI therapy results in short-lived and heterogeneous responses. [electronic resource]
Producer: 20190912Description: 130-134 p. digitalISSN:- 1872-8332
- Aged
- Anaplastic Lymphoma Kinase -- antagonists & inhibitors
- Carcinoma, Non-Small-Cell Lung -- drug therapy
- Crizotinib -- pharmacology
- Drug Resistance, Neoplasm
- ErbB Receptors -- antagonists & inhibitors
- Female
- Gene Amplification
- Humans
- Lung Neoplasms -- drug therapy
- Male
- Middle Aged
- Mutation -- genetics
- Protein Kinase Inhibitors -- therapeutic use
- Proto-Oncogene Proteins c-met -- antagonists & inhibitors
- Survival Analysis
- Treatment Outcome
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Publication Type: Journal Article
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