Crizotinib treatment for patients with EGFR mutation positive NSCLC that acquire cMET amplification after EGFR TKI therapy results in short-lived and heterogeneous responses.
van Veggel, Bianca
Crizotinib treatment for patients with EGFR mutation positive NSCLC that acquire cMET amplification after EGFR TKI therapy results in short-lived and heterogeneous responses. [electronic resource] - Lung cancer (Amsterdam, Netherlands) 10 2018 - 130-134 p. digital
Publication Type: Journal Article
1872-8332
10.1016/j.lungcan.2018.07.030 doi
Aged
Anaplastic Lymphoma Kinase--antagonists & inhibitors
Carcinoma, Non-Small-Cell Lung--drug therapy
Crizotinib--pharmacology
Drug Resistance, Neoplasm
ErbB Receptors--antagonists & inhibitors
Female
Gene Amplification
Humans
Lung Neoplasms--drug therapy
Male
Middle Aged
Mutation--genetics
Protein Kinase Inhibitors--therapeutic use
Proto-Oncogene Proteins c-met--antagonists & inhibitors
Survival Analysis
Treatment Outcome
Crizotinib treatment for patients with EGFR mutation positive NSCLC that acquire cMET amplification after EGFR TKI therapy results in short-lived and heterogeneous responses. [electronic resource] - Lung cancer (Amsterdam, Netherlands) 10 2018 - 130-134 p. digital
Publication Type: Journal Article
1872-8332
10.1016/j.lungcan.2018.07.030 doi
Aged
Anaplastic Lymphoma Kinase--antagonists & inhibitors
Carcinoma, Non-Small-Cell Lung--drug therapy
Crizotinib--pharmacology
Drug Resistance, Neoplasm
ErbB Receptors--antagonists & inhibitors
Female
Gene Amplification
Humans
Lung Neoplasms--drug therapy
Male
Middle Aged
Mutation--genetics
Protein Kinase Inhibitors--therapeutic use
Proto-Oncogene Proteins c-met--antagonists & inhibitors
Survival Analysis
Treatment Outcome