Tyrosine Phosphorylation of Mitochondrial Creatine Kinase 1 Enhances a Druggable Tumor Energy Shuttle Pathway. [electronic resource]
Producer: 20191022Description: 833-847.e8 p. digitalISSN:- 1932-7420
- Animals
- Antineoplastic Agents -- therapeutic use
- Antineoplastic Combined Chemotherapy Protocols -- therapeutic use
- Breast Neoplasms -- metabolism
- Cell Line, Tumor
- Cell Transformation, Neoplastic
- Creatine Kinase -- genetics
- Creatinine -- analogs & derivatives
- Drug Resistance, Neoplasm
- Energy Metabolism
- Energy Transfer
- Female
- Gene Knockdown Techniques
- Humans
- Lapatinib -- therapeutic use
- Mice
- Mice, Nude
- Mitochondria -- metabolism
- Mitochondrial Proteins -- metabolism
- Phosphocreatine -- metabolism
- Phosphorylation
- Receptor, ErbB-2 -- metabolism
- Trastuzumab -- therapeutic use
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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