Tyrosine Phosphorylation of Mitochondrial Creatine Kinase 1 Enhances a Druggable Tumor Energy Shuttle Pathway.

Kurmi, Kiran

Tyrosine Phosphorylation of Mitochondrial Creatine Kinase 1 Enhances a Druggable Tumor Energy Shuttle Pathway. [electronic resource] - Cell metabolism 12 2018 - 833-847.e8 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1932-7420

10.1016/j.cmet.2018.08.008 doi


Animals
Antineoplastic Agents--therapeutic use
Antineoplastic Combined Chemotherapy Protocols--therapeutic use
Breast Neoplasms--metabolism
Cell Line, Tumor
Cell Transformation, Neoplastic
Creatine Kinase--genetics
Creatinine--analogs & derivatives
Drug Resistance, Neoplasm
Energy Metabolism
Energy Transfer
Female
Gene Knockdown Techniques
Humans
Lapatinib--therapeutic use
Mice
Mice, Nude
Mitochondria--metabolism
Mitochondrial Proteins--metabolism
Phosphocreatine--metabolism
Phosphorylation
Receptor, ErbB-2--metabolism
Trastuzumab--therapeutic use
Xenograft Model Antitumor Assays