Long noncoding RNA HOTAIR promotes the self-renewal of leukemia stem cells through epigenetic silencing of p15. [electronic resource]
Producer: 20190225Description: 32-40.e3 p. digitalISSN:- 1873-2399
- Animals
- Bone Marrow Transplantation
- Cell Self Renewal -- physiology
- Cell Transformation, Neoplastic -- genetics
- Cyclin-Dependent Kinase Inhibitor p15 -- antagonists & inhibitors
- Enhancer of Zeste Homolog 2 Protein -- physiology
- Gene Expression Regulation, Leukemic
- Gene Knockdown Techniques
- Gene Silencing
- Heterografts
- Histone Code -- genetics
- Humans
- Leukemia, Myeloid, Acute -- genetics
- Mice
- Molecular Targeted Therapy
- Neoplastic Stem Cells -- cytology
- Oncogene Proteins, Fusion -- genetics
- Promoter Regions, Genetic
- RNA, Long Noncoding -- physiology
- RNA, Neoplasm -- physiology
- Tumor Stem Cell Assay
- U937 Cells
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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