Long noncoding RNA HOTAIR promotes the self-renewal of leukemia stem cells through epigenetic silencing of p15.
Gao, Shenmeng
Long noncoding RNA HOTAIR promotes the self-renewal of leukemia stem cells through epigenetic silencing of p15. [electronic resource] - Experimental hematology 11 2018 - 32-40.e3 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1873-2399
10.1016/j.exphem.2018.08.005 doi
Animals
Bone Marrow Transplantation
Cell Self Renewal--physiology
Cell Transformation, Neoplastic--genetics
Cyclin-Dependent Kinase Inhibitor p15--antagonists & inhibitors
Enhancer of Zeste Homolog 2 Protein--physiology
Gene Expression Regulation, Leukemic
Gene Knockdown Techniques
Gene Silencing
Heterografts
Histone Code--genetics
Humans
Leukemia, Myeloid, Acute--genetics
Mice
Molecular Targeted Therapy
Neoplastic Stem Cells--cytology
Oncogene Proteins, Fusion--genetics
Promoter Regions, Genetic
RNA, Long Noncoding--physiology
RNA, Neoplasm--physiology
Tumor Stem Cell Assay
U937 Cells
Long noncoding RNA HOTAIR promotes the self-renewal of leukemia stem cells through epigenetic silencing of p15. [electronic resource] - Experimental hematology 11 2018 - 32-40.e3 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1873-2399
10.1016/j.exphem.2018.08.005 doi
Animals
Bone Marrow Transplantation
Cell Self Renewal--physiology
Cell Transformation, Neoplastic--genetics
Cyclin-Dependent Kinase Inhibitor p15--antagonists & inhibitors
Enhancer of Zeste Homolog 2 Protein--physiology
Gene Expression Regulation, Leukemic
Gene Knockdown Techniques
Gene Silencing
Heterografts
Histone Code--genetics
Humans
Leukemia, Myeloid, Acute--genetics
Mice
Molecular Targeted Therapy
Neoplastic Stem Cells--cytology
Oncogene Proteins, Fusion--genetics
Promoter Regions, Genetic
RNA, Long Noncoding--physiology
RNA, Neoplasm--physiology
Tumor Stem Cell Assay
U937 Cells