A predicted unstructured C-terminal loop domain in SIRT1 is required for cathepsin B cleavage. [electronic resource]
Producer: 20191125ISSN:- 1477-9137
- Animals
- Cathepsin B -- metabolism
- Cellular Senescence -- physiology
- Computational Biology
- Female
- HEK293 Cells
- HeLa Cells
- Humans
- Male
- Mice
- Mice, 129 Strain
- Mice, Transgenic
- Protein Interaction Domains and Motifs -- genetics
- Protein Isoforms -- chemistry
- Protein Structure, Secondary
- Proteolysis
- Sirtuin 1 -- chemistry
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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