A predicted unstructured C-terminal loop domain in SIRT1 is required for cathepsin B cleavage.

Kumar, Ashok

A predicted unstructured C-terminal loop domain in SIRT1 is required for cathepsin B cleavage. [electronic resource] - Journal of cell science 08 2018

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1477-9137

10.1242/jcs.214973 doi


Animals
Cathepsin B--metabolism
Cellular Senescence--physiology
Computational Biology
Female
HEK293 Cells
HeLa Cells
Humans
Male
Mice
Mice, 129 Strain
Mice, Transgenic
Protein Interaction Domains and Motifs--genetics
Protein Isoforms--chemistry
Protein Structure, Secondary
Proteolysis
Sirtuin 1--chemistry