A sodium-glucose cotransporter 2 inhibitor attenuates renal capillary injury and fibrosis by a vascular endothelial growth factor-dependent pathway after renal injury in mice. [electronic resource]
Producer: 20190606Description: 524-535 p. digitalISSN:- 1523-1755
- Acute Kidney Injury -- drug therapy
- Angiogenesis Inhibitors -- pharmacology
- Animals
- Blood Glucose -- metabolism
- Capillaries -- drug effects
- Disease Models, Animal
- Drug Evaluation, Preclinical
- Fibrosis
- Gene Knockdown Techniques
- Glucose Transporter Type 2 -- genetics
- Humans
- Kidney Tubules, Proximal -- blood supply
- Male
- Mice
- Mice, Inbred C57BL
- Receptors, Vascular Endothelial Growth Factor -- antagonists & inhibitors
- Reperfusion Injury -- complications
- Sodium-Glucose Transporter 2 -- metabolism
- Sodium-Glucose Transporter 2 Inhibitors -- pharmacology
- Sorbitol -- analogs & derivatives
- Sunitinib -- pharmacology
- Treatment Outcome
- Vascular Endothelial Growth Factor A -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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