Genome-wide CRISPR-KO Screen Uncovers mTORC1-Mediated Gsk3 Regulation in Naive Pluripotency Maintenance and Dissolution. [electronic resource]
Producer: 20191107Description: 489-502 p. digitalISSN:- 2211-1247
- Animals
- Cell Differentiation -- genetics
- Cell Self Renewal
- Clustered Regularly Interspaced Short Palindromic Repeats -- genetics
- Gene Expression Regulation, Developmental
- Gene Knockout Techniques
- Genome
- Glycogen Synthase Kinase 3 -- metabolism
- Mechanistic Target of Rapamycin Complex 1 -- metabolism
- Mice
- Mice, Knockout
- Models, Biological
- Mouse Embryonic Stem Cells
- Phenotype
- Pluripotent Stem Cells -- cytology
- Transcriptome -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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