Genome-wide CRISPR-KO Screen Uncovers mTORC1-Mediated Gsk3 Regulation in Naive Pluripotency Maintenance and Dissolution.

Li, Meng

Genome-wide CRISPR-KO Screen Uncovers mTORC1-Mediated Gsk3 Regulation in Naive Pluripotency Maintenance and Dissolution. [electronic resource] - Cell reports 07 2018 - 489-502 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

2211-1247

10.1016/j.celrep.2018.06.027 doi


Animals
Cell Differentiation--genetics
Cell Self Renewal
Clustered Regularly Interspaced Short Palindromic Repeats--genetics
Gene Expression Regulation, Developmental
Gene Knockout Techniques
Genome
Glycogen Synthase Kinase 3--metabolism
Mechanistic Target of Rapamycin Complex 1--metabolism
Mice
Mice, Knockout
Models, Biological
Mouse Embryonic Stem Cells
Phenotype
Pluripotent Stem Cells--cytology
Transcriptome--genetics