Somatic mutation profiling of vulvar cancer: Exploring therapeutic targets. [electronic resource]
Producer: 20181026Description: 552-561 p. digitalISSN:- 1095-6859
- AMP-Activated Protein Kinase Kinases
- Adult
- Aged
- Aged, 80 and over
- Antibiotics, Antineoplastic -- pharmacology
- Antineoplastic Agents -- pharmacology
- Benzamides
- Carcinoma, Squamous Cell -- genetics
- Cell Line, Tumor
- Cell Survival -- drug effects
- Class I Phosphatidylinositol 3-Kinases -- genetics
- Cyclin-Dependent Kinase Inhibitor p16
- Cyclin-Dependent Kinase Inhibitor p18 -- genetics
- DNA Mutational Analysis
- DNA, Neoplasm -- analysis
- Disease-Free Survival
- Everolimus -- pharmacology
- F-Box-WD Repeat-Containing Protein 7 -- genetics
- Female
- GTP-Binding Protein alpha Subunits, Gq-G11 -- genetics
- High-Throughput Nucleotide Sequencing
- Humans
- Janus Kinase 3 -- genetics
- Middle Aged
- Morpholines -- pharmacology
- Mutation
- PTEN Phosphohydrolase -- genetics
- Papillomaviridae
- Papillomavirus Infections -- complications
- Phosphatidylinositol 3-Kinase -- metabolism
- Protein Kinase Inhibitors -- pharmacology
- Protein Serine-Threonine Kinases -- genetics
- Proto-Oncogene Proteins c-akt -- genetics
- Proto-Oncogene Proteins p21(ras) -- genetics
- Pyrimidines
- Receptor, Fibroblast Growth Factor, Type 3 -- genetics
- Signal Transduction -- drug effects
- Sirolimus -- pharmacology
- Smad4 Protein -- genetics
- TOR Serine-Threonine Kinases -- metabolism
- Tumor Suppressor Protein p53 -- genetics
- Vulvar Neoplasms -- genetics
- fms-Like Tyrosine Kinase 3 -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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