Somatic mutation profiling of vulvar cancer: Exploring therapeutic targets.
Zięba, Sebastian
Somatic mutation profiling of vulvar cancer: Exploring therapeutic targets. [electronic resource] - Gynecologic oncology 09 2018 - 552-561 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1095-6859
10.1016/j.ygyno.2018.06.026 doi
AMP-Activated Protein Kinase Kinases
Adult
Aged
Aged, 80 and over
Antibiotics, Antineoplastic--pharmacology
Antineoplastic Agents--pharmacology
Benzamides
Carcinoma, Squamous Cell--genetics
Cell Line, Tumor
Cell Survival--drug effects
Class I Phosphatidylinositol 3-Kinases--genetics
Cyclin-Dependent Kinase Inhibitor p16
Cyclin-Dependent Kinase Inhibitor p18--genetics
DNA Mutational Analysis
DNA, Neoplasm--analysis
Disease-Free Survival
Everolimus--pharmacology
F-Box-WD Repeat-Containing Protein 7--genetics
Female
GTP-Binding Protein alpha Subunits, Gq-G11--genetics
High-Throughput Nucleotide Sequencing
Humans
Janus Kinase 3--genetics
Middle Aged
Morpholines--pharmacology
Mutation
PTEN Phosphohydrolase--genetics
Papillomaviridae
Papillomavirus Infections--complications
Phosphatidylinositol 3-Kinase--metabolism
Protein Kinase Inhibitors--pharmacology
Protein Serine-Threonine Kinases--genetics
Proto-Oncogene Proteins c-akt--genetics
Proto-Oncogene Proteins p21(ras)--genetics
Pyrimidines
Receptor, Fibroblast Growth Factor, Type 3--genetics
Signal Transduction--drug effects
Sirolimus--pharmacology
Smad4 Protein--genetics
TOR Serine-Threonine Kinases--metabolism
Tumor Suppressor Protein p53--genetics
Vulvar Neoplasms--genetics
fms-Like Tyrosine Kinase 3--genetics
Somatic mutation profiling of vulvar cancer: Exploring therapeutic targets. [electronic resource] - Gynecologic oncology 09 2018 - 552-561 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1095-6859
10.1016/j.ygyno.2018.06.026 doi
AMP-Activated Protein Kinase Kinases
Adult
Aged
Aged, 80 and over
Antibiotics, Antineoplastic--pharmacology
Antineoplastic Agents--pharmacology
Benzamides
Carcinoma, Squamous Cell--genetics
Cell Line, Tumor
Cell Survival--drug effects
Class I Phosphatidylinositol 3-Kinases--genetics
Cyclin-Dependent Kinase Inhibitor p16
Cyclin-Dependent Kinase Inhibitor p18--genetics
DNA Mutational Analysis
DNA, Neoplasm--analysis
Disease-Free Survival
Everolimus--pharmacology
F-Box-WD Repeat-Containing Protein 7--genetics
Female
GTP-Binding Protein alpha Subunits, Gq-G11--genetics
High-Throughput Nucleotide Sequencing
Humans
Janus Kinase 3--genetics
Middle Aged
Morpholines--pharmacology
Mutation
PTEN Phosphohydrolase--genetics
Papillomaviridae
Papillomavirus Infections--complications
Phosphatidylinositol 3-Kinase--metabolism
Protein Kinase Inhibitors--pharmacology
Protein Serine-Threonine Kinases--genetics
Proto-Oncogene Proteins c-akt--genetics
Proto-Oncogene Proteins p21(ras)--genetics
Pyrimidines
Receptor, Fibroblast Growth Factor, Type 3--genetics
Signal Transduction--drug effects
Sirolimus--pharmacology
Smad4 Protein--genetics
TOR Serine-Threonine Kinases--metabolism
Tumor Suppressor Protein p53--genetics
Vulvar Neoplasms--genetics
fms-Like Tyrosine Kinase 3--genetics