Targeting EZH2 Reprograms Intratumoral Regulatory T Cells to Enhance Cancer Immunity. [electronic resource]
Producer: 20191105Description: 3262-3274 p. digitalISSN:- 2211-1247
- Animals
- CD4-Positive T-Lymphocytes -- cytology
- CD8-Positive T-Lymphocytes -- cytology
- Cell Line, Tumor
- Enhancer of Zeste Homolog 2 Protein -- deficiency
- Forkhead Transcription Factors -- metabolism
- Humans
- Interferon-gamma -- metabolism
- Lymphocytes, Tumor-Infiltrating -- cytology
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Neoplasms -- immunology
- T-Lymphocytes, Regulatory -- cytology
- Tumor Microenvironment
- Tumor Necrosis Factor-alpha -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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