Enhanced mitochondrial DNA repair of the common disease-associated variant, Ser326Cys, of hOGG1 through small molecule intervention. [electronic resource]
Producer: 20191001Description: 149-162 p. digitalISSN:- 1873-4596
- A549 Cells
- Animals
- Cells, Cultured
- DNA Damage
- DNA Glycosylases -- genetics
- DNA Repair
- DNA, Mitochondrial -- genetics
- Fibroblasts -- cytology
- Herbicides -- adverse effects
- Humans
- Mice
- Mice, Knockout
- Mitochondria -- drug effects
- Mutation
- Oxidation-Reduction
- Oxidative Stress -- drug effects
- Paraquat -- adverse effects
- Reactive Oxygen Species -- metabolism
- Serine -- genetics
- Small Molecule Libraries -- pharmacology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
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