Cardiac fibrosis can be attenuated by blocking the activity of transglutaminase 2 using a selective small-molecule inhibitor. [electronic resource]
Producer: 20191129Description: 613 p. digitalISSN:- 2041-4889
- Angiotensin II
- Animals
- Collagen -- metabolism
- Dipeptides -- metabolism
- Disease Models, Animal
- Fibrosis
- GTP-Binding Proteins -- antagonists & inhibitors
- Human Umbilical Vein Endothelial Cells -- drug effects
- Humans
- Mice
- Myocardium -- pathology
- Myofibroblasts -- drug effects
- Protein Glutamine gamma Glutamyltransferase 2
- Small Molecule Libraries -- pharmacology
- Transforming Growth Factor beta1 -- pharmacology
- Transglutaminases -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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