RNF12 X-Linked Intellectual Disability Mutations Disrupt E3 Ligase Activity and Neural Differentiation. [electronic resource]
Producer: 20191209Description: 1599-1611 p. digitalISSN:- 2211-1247
- Animals
- Biocatalysis
- CRISPR-Cas Systems
- Cell Differentiation -- genetics
- Cell Nucleus -- metabolism
- Gene Silencing
- Genes, X-Linked
- Humans
- Intellectual Disability -- genetics
- Male
- Mice
- Mutation -- genetics
- Neural Stem Cells -- metabolism
- Neurons -- metabolism
- Protein Multimerization
- Protein Stability
- Proteolysis
- Substrate Specificity
- Ubiquitin -- metabolism
- Ubiquitin-Protein Ligases -- genetics
- Ubiquitination
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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