Bergamot natural products eradicate cancer stem cells (CSCs) by targeting mevalonate, Rho-GDI-signalling and mitochondrial metabolism. [electronic resource]
Producer: 20181108Description: 984-996 p. digitalISSN:- 0005-2728
- Apoptosis -- drug effects
- Biological Products -- pharmacology
- Biomarkers, Tumor -- metabolism
- Breast Neoplasms -- drug therapy
- Cell Proliferation -- drug effects
- Cells, Cultured
- Female
- Fibroblasts -- cytology
- Gene Expression Regulation, Neoplastic -- drug effects
- Humans
- Hydroxymethylglutaryl CoA Reductases -- metabolism
- Mevalonic Acid -- metabolism
- Mitochondria -- drug effects
- Neoplasm Metastasis
- Neoplastic Stem Cells -- drug effects
- Plant Oils -- chemistry
- Prognosis
- Signal Transduction -- drug effects
- Survival Rate
- rho-Specific Guanine Nucleotide Dissociation Inhibitors -- metabolism
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Publication Type: Journal Article
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