Accurate detection and quantification of epigenetic and genetic second hits in BRCA1 and BRCA2-associated hereditary breast and ovarian cancer reveals multiple co-acting second hits. [electronic resource]
Producer: 20190611Description: 125-133 p. digitalISSN:- 1872-7980
- BRCA1 Protein -- genetics
- BRCA2 Protein -- genetics
- Cohort Studies
- DNA Copy Number Variations
- DNA Methylation
- Epigenesis, Genetic
- Female
- Germ-Line Mutation
- Hereditary Breast and Ovarian Cancer Syndrome -- genetics
- Humans
- Loss of Heterozygosity
- Models, Theoretical
- Point Mutation
- Promoter Regions, Genetic
- Sequence Analysis, DNA -- methods
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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