Accurate detection and quantification of epigenetic and genetic second hits in BRCA1 and BRCA2-associated hereditary breast and ovarian cancer reveals multiple co-acting second hits.
Van Heetvelde, Mattias
Accurate detection and quantification of epigenetic and genetic second hits in BRCA1 and BRCA2-associated hereditary breast and ovarian cancer reveals multiple co-acting second hits. [electronic resource] - Cancer letters 07 2018 - 125-133 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1872-7980
10.1016/j.canlet.2018.03.026 doi
BRCA1 Protein--genetics
BRCA2 Protein--genetics
Cohort Studies
DNA Copy Number Variations
DNA Methylation
Epigenesis, Genetic
Female
Germ-Line Mutation
Hereditary Breast and Ovarian Cancer Syndrome--genetics
Humans
Loss of Heterozygosity
Models, Theoretical
Point Mutation
Promoter Regions, Genetic
Sequence Analysis, DNA--methods
Accurate detection and quantification of epigenetic and genetic second hits in BRCA1 and BRCA2-associated hereditary breast and ovarian cancer reveals multiple co-acting second hits. [electronic resource] - Cancer letters 07 2018 - 125-133 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1872-7980
10.1016/j.canlet.2018.03.026 doi
BRCA1 Protein--genetics
BRCA2 Protein--genetics
Cohort Studies
DNA Copy Number Variations
DNA Methylation
Epigenesis, Genetic
Female
Germ-Line Mutation
Hereditary Breast and Ovarian Cancer Syndrome--genetics
Humans
Loss of Heterozygosity
Models, Theoretical
Point Mutation
Promoter Regions, Genetic
Sequence Analysis, DNA--methods