Reactivation of Mutant-EGFR Degradation through Clathrin Inhibition Overcomes Resistance to EGFR Tyrosine Kinase Inhibitors. [electronic resource]
Producer: 20190730Description: 3267-3279 p. digitalISSN:- 1538-7445
- Antineoplastic Combined Chemotherapy Protocols -- pharmacology
- Apoptosis -- drug effects
- Carcinoma, Non-Small-Cell Lung -- drug therapy
- Cell Line, Tumor
- Clathrin -- antagonists & inhibitors
- Drug Resistance, Neoplasm -- drug effects
- Endocytosis -- drug effects
- ErbB Receptors -- genetics
- Humans
- Lung Neoplasms -- drug therapy
- Lysosomes -- metabolism
- Mutation
- Protein Kinase Inhibitors -- pharmacology
- Proteolysis -- drug effects
- Signal Transduction -- genetics
- Sulfonamides -- pharmacology
- Thiazolidines -- pharmacology
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Publication Type: Journal Article
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